Revista Bio Ciencias

Multidisciplinary management of paraquat poisoning in pregnant patients: Case report

Daniela Alejandra Pérez Díaz — 2025-06-10

Paraquat is an agricultural pesticide from the bipyridyl group with toxic effects on several organs. We present the case of a 15-year-old patient with a 16-week gestation pregnancy who accidentally ingested liquid paraquat. The patient had a history of self-inflicted injuries (cutting). During her hospital stay, she developed hepatorenal damage and pulmonary fibrosis, with a favorable outcome following treatment with supplemental oxygen and corticosteroids. A multidisciplinary approach was taken, including the ethics and bioethics committee, and the pregnancy concluded successfully. Mental health treatment was initiated. We emphasize the importance of identifying risk factors for both physical and psychological health in the care of children and adolescents.

Jejunal volvulus as an uncommon cause of intestinal occlusion, case report.

Viriidiana Montserrath Pineda García — 2025-06-02

Midgut volvulus is a significant surgical condition in pediatric practice. However, although its incidence in adults is low, it can occur in this age group, with predominant risk factors such as adhesions secondary to previous abdominal surgeries. Computed tomography, a widely accessible imaging study today, plays a key role in diagnosis, although it is not the definitive method. Among its suggestive findings, the 'whirlpool sign' stands out. This report presents the case of an octogenarian patient with a history of abdominal surgery who developed a jejunal volvulus, a condition rarely documented in the medical literature. Emphasis is placed on her clinical presentation, key diagnostic findings, and therapeutic approach.

Diagnostic dilemma in an adolescent with a femoral mass

Javier Guzmán Carranza — 2025-03-07

This case involves a 16-year-old male adolescent who presented with intermittent pain in the left knee, worsened by physical activity and accompanied by persistent swelling. Despite initial treatment with analgesics and a splint, symptoms persisted, prompting an MRI that revealed a soft tissue mass in the distal third of the left thigh, compatible with parosteal osteosarcoma or pigmented villonodular synovitis. Subsequently, a surgical biopsy was performed to confirm the diagnosis. During the procedure, bone infiltration was observed, and the samples taken confirmed malignant osteosarcoma. The patient started chemotherapy under the EURAMOS protocol, achieving a significant tumor reduction of 60%.

This case highlights the importance of a multidisciplinary approach and precise differential diagnosis in young patients presenting with bone masses. The combination of imaging and biopsy was crucial in distinguishing between osteosarcoma and pigmented villonodular synovitis, two entities with very different treatments and prognoses. The case emphasizes the need to suspect malignancy in patients with persistent knee pain and swelling, even when a benign condition is initially considered. Rapid intervention and targeted treatment resulted in a favorable short-term response, underscoring the importance of early detection and management in the prognosis of these tumors. This case provides valuable insights into the management and diagnosis of bone lesions in adolescents.