Revista Bio Ciencias https://revistabiociencias.uan.edu.mx/index.php/BIOCIENCIAS <p><strong><em>Revista Bio Ciencias</em></strong> is an electronic publication, refereed and indexed that disseminates technical quality information in Agriculture and Biologic areas. The <strong>aim and scope</strong> of Revista Bio Ciencias is to promote a space of reflection regarding current paradigms and tendencies in biological sciences, the latter from disciplinary, inter-disciplinary and trans-disciplinary approaches. Hence, the main areas of interest of the journal are: environmental sciences, veterinary, zootechnics as well as aquaculture/fishing and agriculture. Researches approaching socio-economic issues related to agricultural productive chains are also welcome.</p><p>Revista Bio Ciencias is published three times a year, and manuscripts reception is open permanently all year. Manuscripts are published in formats of <strong>original articles, revision articles </strong>(only by invitation)<strong>, brief articles, case reports, technical reports, editorials, news and letters to the editor.</strong></p><p><strong><em>Revista Bio Ciencias</em></strong> is found within the following indexes: <strong>classification system of Mexican journals of science and technology (CONACYT index),</strong> <strong>Web of Science (Emerging Source), DOAJ, Latindex and Imbiomed. DOI: 10.15741/revbio</strong>.</p><p id="yui_3_16_0_1_1408635784931_2099" class="yiv3960191530MsoNormal">Revista Bio Ciencias is an open access forum in which there are no Article Processing Charges (APC) nor for publishing; nonetheless, from March 15th 2018, authors can submit articles in English or Spanish. <strong>Once articles have been accepted for publication</strong>, authors must complement their submission in both languages (Spanish/English), or else they must declare that they wish to have the translation made with one of our certified expert translators, who will be in direct contact with the authors for the translation process, and this will have an approximate cost of $100 USD (one hundred American dollars).</p><p><span lang="EN-US">Ethical principles: Revista Bio Ciencias receives manuscripts under predujice of good repute of authors; hence, all information is published under their responsibility. Starting the year 2017, the journal will use the program Turnitin as plagarism prevention service. In case an author is detected to have committed plagiarism, he will be banned from Revista Bio Ciencias and the published article will be withdrawn.</span></p><span lang="EN-US"><br /></span> es-ES <a href="http://creativecommons.org/licenses/by-nc-nd/3.0/deed.es" rel="license"><img src="http://i.creativecommons.org/l/by-nc-nd/3.0/88x31.png" alt="Licencia Creative Commons" /></a><br /><span>Revista Bio Ciencias by</span> <a href="http://biociencias.uan.edu.mx/" rel="cc:attributionURL">Universidad Autónoma de Nayarit</a> under <a href="http://creativecommons.org/licenses/by-nc/3.0/" rel="license">Creative Commons Attribution-NonCommercial 3.0 Unported License</a>.<br />Based on work of <a href="http://biociencias.uan.edu.mx/" rel="dct:source">http://biociencias.uan.edu.mx/</a>.<br />Further permits not covered by this licence can be found at <a href="/index.php/BIOCIENCIAS" rel="cc:morePermissions">http://editorial.uan.edu.mx/index.php/BIOCIENCIAS</a>. biociencias@uan.edu.mx (Dra. Karina J. G. Díaz Resendiz) revistabiociencias@yahoo.com.mx (Mercedes Zambrano Soria) Mon, 07 Apr 2025 10:32:08 -0700 OJS 3.3.0.11 http://blogs.law.harvard.edu/tech/rss 60 Diagnostic dilemma in an adolescent with a femoral mass https://revistabiociencias.uan.edu.mx/index.php/BIOCIENCIAS/article/view/1803 <p>This case involves a 16-year-old male adolescent who presented with intermittent pain in the left knee, worsened by physical activity and accompanied by persistent swelling. Despite initial treatment with analgesics and a splint, symptoms persisted, prompting an MRI that revealed a soft tissue mass in the distal third of the left thigh, compatible with parosteal osteosarcoma or pigmented villonodular synovitis. Subsequently, a surgical biopsy was performed to confirm the diagnosis. During the procedure, bone infiltration was observed, and the samples taken confirmed malignant osteosarcoma. The patient started chemotherapy under the EURAMOS protocol, achieving a significant tumor reduction of 60%.</p> <p>This case highlights the importance of a multidisciplinary approach and precise differential diagnosis in young patients presenting with bone masses. The combination of imaging and biopsy was crucial in distinguishing between osteosarcoma and pigmented villonodular synovitis, two entities with very different treatments and prognoses. The case emphasizes the need to suspect malignancy in patients with persistent knee pain and swelling, even when a benign condition is initially considered. Rapid intervention and targeted treatment resulted in a favorable short-term response, underscoring the importance of early detection and management in the prognosis of these tumors. This case provides valuable insights into the management and diagnosis of bone lesions in adolescents.</p> <p>&nbsp;</p> Javier Guzmán Carranza, Daniela Alejandra Pérez Díaz, E. G. González Salinas Copyright (c) 2025 Revista Bio Ciencias https://revistabiociencias.uan.edu.mx/index.php/BIOCIENCIAS/article/view/1803 Fri, 07 Mar 2025 00:00:00 -0700