Eclosion inhibition of Haemonchus contortus eggs with two extracts of Caesalpinia coriaria fruits

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Haemonchus contortus is a gastrointestinal parasite of small ruminants. The objective was to evaluate the effect of the acetonic and ethanolic extract of the Caesalpinia ciriaria fruits on the egg hatching inhibition (EHI) of Haemonchus contortus in small ruminants. The inhibition effect of hatching was evaluated at different concentrations of the extracts (acetonic: 20.0, 10.0, 5.0, 2.5, 1.2 and 0.6 mg / mL), (ethanolic: 6.15, 3.12, 1.56 and 0.78 mg / mL) and methanol to the 4% with distilled water as negative control and 0.5% ivermectin as positive control, were used. The ovicidal effect data were analyzed with a completely randomized design by analysis of variance using the general linear model and the tukey test (P <0.05); the lethal concentrations (LC50 and LC90) were estimated by the Probit analysis of the statistical analysis systems (SAS) program. Concentration dosage depended extracts effects, were observed, where the ovicidal activity was comparatively similar to the positive control to the doses of 1.2 mg / mL for the acetonic extract (AE) and 0.78 mg / mL for the ethanolic extract (EE), respectively (P <0.0001). The LC50 were AE = 0.23 mg / mL and EE = 0.014 mg / mL; LC90 AE = 1.04 mg / mL and EE = 0.14 mg / mL, for each extract, respectively. The results indicate that the EHI of the extracts elaborated with the C. coriaria fruits in acetonic and ethanolic solvent extract secondary compounds that have activity against H. contortus eggs, nevertheless, requires of greater investigations as antiparasitic for its direct animal use

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